Two things to look into
1. New Group AI with 2 identical champions
My observation is that if you have 2 of the same champion and prioritize A3 as #1 and A2 as #2 then for the second copy of the same champ do the reverse: A2 is #1 and A3 is #2. Then programming of the second copy is ignored. They both use A3 first and then A2. For me this is happening with Lix but I assume it might be general. Could be something I did, but worth looking into.
2. In Doomtower - fighting Krisks - Using Cardiel which I think is relevant for the irremovable rez on death buff - I'm sometimes seeing a Decrease defense buff (the one from Krisk's passive) get stuck in the first position and never coming off or get removed. If you look at Info it isn't actually being applied, but the icon is stuck over the character. It looks like this has something to do with the rez on death from Cardiel but its sporadic so maybe tough to reproduce.