If  you  get  Yoshi,  maybe  he  could  help  you  by  bringing  another  source  of  HP  Burn,  along  with  Increase  ACC  and  Decrease  ACC.

I actually have yoshi ready to be fused. But he hits random enemies so he can grant healing to the spider. And spider debuffs cannot be resisted so yoshi's buffs doesnt matter. Or am I mistaken ? 

Nevertheless accuracy is not my problem. somehow I cant survive  the run... 

Oh  i  thought  you  were  talking  about  the  Frost  Spider,  my  mistake.  You  should  focuse  on  using  a  cleanser  such  as  your  Grizzled  Jarl  because  he  also  brings  Heal  Reduction  which  allows  you  to  take  on  the  Spiderlings,  without  them  helaing  the  spider.  Then  Drexthar  should  be  able  to  HP  Burn  them  to  kill  the  main  spider,  or  you  could  use  Turn  Meter  control  like  Alure,  Armiger,  or  Coldheart  along  with  a  constant  healer  like  Scyl  or  Doompriest to  slowly  but  surely  take  them  down.

replace grush with arbiter.  drex, scyl, arbiter, maus mage, doom

you may have to manual as arbiter and maus mage AI is iffy...

and you are correct anyone with random attacks is not good

I was also thinking about a pure damage comp since I have mashalled who can lock the healing. Maybe Mashalled, scyl/iron brago, Draco/stag knight, mausoleum, arbiter

I used similar comp to yours 

Scyll - 60k hp, 4k def, 240 speed in relentless

RQ tender - 70k hp, 4k def, 230 speed

DP - 50k hp , 4k def, 270 speed

MM - 80k hp, 3k def, 240 speed

Drex - 400 acc (320 + lead), 5k def, 30k hp, 180 speed (full DPS build - don't think it matters tho)

Not sure if this can help you in any way but with these gears it was super easy

I haven't reached Floor 90 of the Nether Spider.

I don't know if the Strategy I use would work against it or not.

The set up I used last time was the following:

- Frozen Banshee

- Roschard the Tower

- Vrask

- M.Mage

- Zelotah

Have you considered trying out a Shield hero on your team?

You do own Zelotah & Lordic.

I wouldn't add Valkyrie because her Shield requires you to attack all enemies.

BUT Zelotah & Lordic don't attack when they do Shields.

Is there a page that mentions all the champs which are good for nether spider? i could not see one on raid codex

Not Really

Hellhades web page has a few heroes which he mentions are good.

Ayumilove web page has a few heroes which he mentions are good.

But there is no Master List of all heroes.

The best thing to do would be to ask players who already beat the Boss your struggling with.

Nether spider is killing me faster than a kid can eat a chocolate. this is my roster: 

i

i

i

which champions would you use?  what is the best team composition that works?

what stats should each of them have? (speed, accuracy, resistance, atk, def)

I am happy to build up champions which are more effective against Nether spider

I managed with arbiter instead of ghrush. but i had to manual it. well, good enough for me xd

Shambhavi I think you dont have champs that will get you through high lvls of nether spider. 

Try Doompriest, spirit host, frozen banshee, speed champ like high khatun, and maybe zelotah ? idk if it would work. You lack healing basicly, and HP burn.
 

@Shambhavi 

You don't need HP Burn to kill the Nether Spider.

You can use Poison as well.

- Frozen Banshee

- Doom Priest

- Zelotah

I'm not sure about the other 2 remaining hero's.

I would try:

- Melga Steelgirdle

- War Priest

How close are you to getting Scyl of Drakes? 

I'm not a huge fan of War Priest.

I would prefer to replace War Priest with Scyl of Drakes

I just don't see Scyl of Drakes on your account.

War Priest seems to be the only healer you own which doesn't AOE Attack or Random Attack.

I am getting Scyl of Drakes in 4 days. I guess I will try with what I have and once I have scyl then I will use her.