So I've been hoarding glyphs since I hit this 40 max glyph mission waiting for CvC, obviously the speed glyphs being most valuable and most important to optimize.

For non-speed glyphs my strategy is:

• 5* acc/res/%s only on GREAT (no bad substats, epic/lego only) 5star items
• 5* flat atk/hp/def -- basically on my best/most used champs
• 6* -- basically any item that will 100% be used

Speed Glyphs:

• 4*, I use on 6star items only
• 5*, I use only on 5star 2x/3x rolls
• 6*, debating only using on 3x roll or better.  Unfortnuately my arbiter (only 315ish) currently has no 3x rolls... I have no 3x rolls on any 6* speed gear... NONE

So do I sit on 6star speed glyphs until I have a worthy item?  

Any other recommendations for optimally using glyphs?

Good news is I have 30k+ in CvC points just from glyphs for tomorrow, estimated cost to use: 9 million silver... ouch